What is the connection between IBS and celiac disease?

June 14, 2025

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What is the connection between IBS and celiac disease?

Irritable Bowel Syndrome (IBS) and celiac disease are two distinct gastrointestinal disorders, but they share overlapping symptoms and can sometimes be confused with each other. Here’s how they are connected:

🔄 Similar Symptoms
Both IBS and celiac disease can cause:

Abdominal pain or cramping

Bloating

Diarrhea or constipation (or both)

Gas and discomfort

This overlap often leads to misdiagnosis, especially if celiac disease is not screened for in people with IBS symptoms.

🧬 Different Causes
IBS is a functional GI disorder—meaning the digestive system looks normal but doesn’t work properly. It has no single cause but may involve stress, gut-brain interaction, altered gut motility, and microbiome changes.

Celiac disease is an autoimmune disorder—triggered by eating gluten (a protein in wheat, barley, and rye). It damages the small intestine’s lining and impairs nutrient absorption.

🧪 Diagnostic Connection
Studies show that some people diagnosed with IBS actually have undiagnosed celiac disease.

Testing for celiac disease is recommended in people with IBS, especially if symptoms include diarrhea or there’s a family history of autoimmune disease.

📉 Treatment Responses
People with celiac disease must follow a strict gluten-free diet for life.

Some people with IBS may also report improvement on a gluten-free diet, but in their case, it might be due to reducing FODMAPs (fermentable carbs) rather than gluten itself.

🔬 Key Distinction
A positive celiac antibody test and intestinal biopsy confirm celiac disease.

IBS is diagnosed by exclusion, based on symptom criteria (Rome IV) after ruling out other conditions.

✅ Summary Table
Feature IBS Celiac Disease
Cause Functional disorder Autoimmune reaction to gluten
Symptoms Bloating, diarrhea, constipation Same, plus fatigue, anemia, weight loss
Diagnosis Based on symptoms, exclusion Blood tests and biopsy
Treatment Diet changes, stress management Gluten-free diet for life
Long-term risks No intestinal damage Intestinal damage, malabsorption

If you or someone you know has persistent IBS-like symptoms, especially with family history of celiac or autoimmune disease, it’s worth getting tested for celiac disease.

Irritable Bowel Syndrome (IBS) is primarily a functional gastrointestinal disorder, meaning it affects how the gut works rather than causing structural damage. However, while IBS doesn’t directly cause serious physical damage to the intestines or lead to conditions like cancer or IBD (e.g., Crohn’s or ulcerative colitis), it can lead to complications or effects in other parts of the body due to its systemic influence. Here’s how:

1. Nutritional Deficiencies
Cause: Some people with IBS avoid certain foods (e.g., dairy, fiber, gluten) to prevent flare-ups.

Effect: This can lead to deficiencies in calcium, vitamin D, B12, iron, and fiber, potentially affecting bone health, energy levels, and immune function.

2. Fatigue
IBS is commonly associated with chronic fatigue, possibly due to disrupted sleep from symptoms or nutrient deficiencies.

There’s also overlap with Chronic Fatigue Syndrome (CFS) in some patients.

3. Mental Health Issues
Anxiety and depression are common in IBS patients. This is both a cause and an effect—gut-brain axis dysfunction may lead to mood disorders, and chronic symptoms can worsen psychological health.

Stress and anxiety can also amplify gut sensitivity.

4. Pelvic Pain and Sexual Dysfunction
Some people, especially women, report pelvic floor dysfunction, pain during intercourse, or urinary urgency, possibly linked to visceral hypersensitivity and muscle tension.

5. Back Pain and Headaches
Though not directly caused by IBS, many patients report non-GI symptoms like back pain, headaches, or fibromyalgia-like symptoms due to nervous system hypersensitivity.

6. Skin Issues
Inflammation, food intolerances, and nutrient deficiencies in IBS may contribute to eczema, acne, or other skin flare-ups in some individuals.

7. Disrupted Sleep
Discomfort, bloating, and frequent bowel urges can cause insomnia or fragmented sleep, leading to worsened symptoms and daytime fatigue.

Summary:
While IBS doesn’t damage organs outside the gut, it can negatively affect multiple body systems through:

Nutrient imbalances

Sleep disruption

Psychological stress

Gut-brain axis dysregulation

If you’re experiencing symptoms beyond the gut, it’s worth discussing with a healthcare provider to ensure nothing else is contributing and to create a holistic management plan.

The Parkinson’s Protocol™ By Jodi KnappThus, the eBook, The Parkinson’s Protocol, educates you regarding the natural and simple ways to minimize the symptoms and delay the development of Parkinson’s effectively and quickly. It will also help your body to repair itself without following a specific diet plan, using costly ingredients or specific equipment. Its 60 days guarantee to return your money allows you to try for once without any risk.